Overweight People Is Prone Of Developing Arthritis 

Those people who are overweight may acquire several health problems such as developing arthritis, a medical expert says. What usually triggers a person to undergo the conflict driven hip replacement from DePuy Orthopeadics, a unit of Johnson & Johnson, is the development of Arthritis which is about 10,100 lawsuits were being filed even after it made a recall in 2010. As as a matter of fact, the orthopedic surgeon who helped design DePuy Implant testifies in California trial To name one is Osteoarthritis (OA), considered as most common form of arthritis and generally affects elderly patients. There are various forms of arthritis which may have an effect on people at a very untimely age, the Medical News Today website reports.

When a person is overweight, he or she is prone of the growth of osteoarthritis in their system. Several research have disclosed a burly linked between body mass index and osteoarthritis of the hip, knee, foot and hand.

However, the mechanism(s) by which obesity contributes to the onset and progression of osteoarthritis are not fully understood.

The strong relationship between body mass index, altered limb alignment, and osteoarthritis of the knee –and the protective effects of weight loss — support the classic proposition that the effects of obesity on the joint are due to increased bio-mechanical loading and related adjustment in step.

However, obesity is now considered to be a low-grade systemic inflammatory disease. Recent studies suggest that metabolic factors associated with obesity alter systemic levels of pro-inflammatory cytokines that are also associated with osteoarthritis.

Thus, the ultimate influence of obesity on osteoarthritis may involve a complex interaction of genetic, metabolic, and bio-mechanical factors. In this respect, mouse models of obesity can provide excellent systems in which to examine causal relationships among these factors. In recent years, there have been surprisingly few reports examining the effects of obesity on osteoarthritis using mouse models.

It is always best to be mindful of becoming fit and healthy which may help a person prevent a chronic disease such as arthritis, of which the excruciating pain may lead to surgery such as hip replacement and about which remains the subject of several hip replacement. For more related information, please click here.

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